Theory and Background

ODS orders DNA fragments based on the similarity of their fingerprints assigned to clones in a library by one of several experimental approaches. The algorithm has been used to map the entire Schizosaccharomyces pombe genome, chromosome IV of the Aspergillus nidulans genome, and a region of a human chromosome 9. The ODS software displays the maps graphically in a variety of formats and prints graphical displays of summary statistics to check the mapping progress, the quality of a physical map and whether or not underlying models of physical mapping are fitting the data.

This example demonstrates how traditional applications can be employed in new ways.

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